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The discovery of NADH goes back to the biochemist Sir Arthur Harden in 1906. Harden and his colleague William Young conducted experiments on yeast to find out how sugar is converted into alcohol. They discovered that the enzyme Zymase produces NADH when it breaks down sugar.

The discovery of NADH helped deepen the understanding of how energy is generated in cells. The coenzyme is necessary to maintain electron transport in the respiratory chain, activate ATP synthesis, and thereby produce energy. NADH acts as a kind of "energy-storage" by accepting electrons during energy production and then donating them to other molecules to boost metabolism.

In summary, the discovery of NADH is an important milestone in biochemistry and has helped deepen our understanding of how energy is produced in cells.

Yes, the coenzyme NADH is vegan. Both
our products NADH RAPID ENERGY and NADH LIPCARE are 100% vegan as
well.

NADH is derived from yeast, which contains very high levels of the oxidized form of NADH, NAD+. This NAD+ is then enzymatically converted into NADH. NADH is 99.9% pure and no longer contains any traces of yeast.

Yes, generally more NADH means more ATP, because NADH (Nicotinamide Adenine Dinucleotide Hydride) is an important molecule in cell respiration, which plays a central role in the electron transport chain process in the mitochondria. NADH serves as an electron and proton donor, initiating the process of oxidative phosphorylation, which leads to the production of ATP (adenosine triphosphate), the primary energy source of the cell.

During glycolysis and the citric acid cycle (also known as the Krebs cycle), NADH is produced from NAD+ by transferring electrons and protons from glucose degradation products and other nutrients to NAD+. The NADH formed in this way then transports the electrons to the electron transport chain in the inner mitochondrial membrane.

In the electron transport chain, NADH molecules donate their electrons, which releases the energy needed to pump protons across the membrane and create a proton gradient. The return of the protons into the mitochondrial matrix via the ATP synthase leads to the production of ATP. Each NADH molecule entering the electron transport chain can theoretically produce up to about 2.5 to 3 ATP molecules, although this value may vary depending on cell condition and conditions.

Consequently, the amount of ATP generated is directly proportional to the amount of NADH available, as long as the other components of the system are functional and sufficient oxygen is available to serve as the final electron acceptor. In conditions where oxygen is limited, such as anaerobic respiration, ATP is produced in a different way that is less efficient and not as dependent on NADH.

The citric acid cycle describes a series of chemical reactions that occur in cells to produce energy. This cycle takes place in the mitochondria and is one of the main ways cells produce energy from food. The cycle begins with a molecule of Acetyl-Coenzyme-A, which is formed from the breakdown of carbohydrates, fats, and proteins. This molecule then enters the citric acid cycle, where it goes through a series of reactions in which, among other things, NADH is formed.

NAD, NADH, and NAD+ are all molecules found in our cells and are part of the natural energy generation of our bodies by breaking down food.

NAD stands for Nicotinamide Adenine Dinucleotide, and NAD+ and NADH are just slightly different forms of this molecule.

Simply put, NAD+ is the "active" form of the molecule involved in processes where the cell consumes energy, whereas NADH is the "reduced" form involved in the body's own processes where energy is generated. So, if you supplement with NADH, you get the more efficient form of NAD. That is why we focus exclusively on NADH in our supplements.

NMN is a precursor of NAD, from which NAD+ or NADH is ultimately formed.

The effects of our Prof. George Birkmayer NADH RAPID can be detected after 15 minutes with several medical-technical devices (such as Heart Rate Variability = HRV) and also on the ergometer (in fitness centers).

Both products contain approximately 55 sprays. If you use 3 sprays per day, the 10 ml bottle will last for 18 days.

NADH RAPID is a tablet that is best placed under the tongue, where it dissolves within 1-2 minutes. The energy-boosting effect of NADH RAPID ENERGY can be detected after 15 minutes with several medical-technical devices. NADH CONSTANT ENERGY is a "swallow tablet" that should be taken with a glass of water on an empty stomach. The NADH in this tablet is absorbed in the intestine, so the onset of action is noticeable after 1–1½ hours. Both products contain 20 mg of NADH per tablet.

For reasons of durability, most tablets are placed in plastic films that have pockets for the tablets. These are then hermetically sealed with an aluminum foil. This container is called a blister.

NADH ARTHROS is designed to build up and regenerate joint cartilage, and its regeneration takes several months according to medical school experience. NADH VISION is used to protect the eye, especially the macula. To recognize the protective effect of NADH VISION, preventive use over several months is necessary.

Based on our more than 20 years of experience with our NADH products, we know that higher doses have led to significantly better and faster effects.

No interactions with medications have been observed in our scientific studies so far.